Download Mobile Compia MM3 Hard Reset File

- Life expectancy - 12 weeks or more from the moment of randomization;

- IIIb or IV stage of NSCLC (TNM classification version 6);

- Presence of at least 1 measurable tumour with a size not less than 1 cm (revealed
with CT slice thickness not more than 5 mm), as defined by modified Response
Evaluation Criteria in Solid Tumors (RECIST) criteria (specifically, no ascites,
pleural, or pericardial effusions, osteoblastic bone metastases, or carcinomatous
lymphangitis of the lung as only lesion;

- BC metastases in central nervous system, progressing or clinically manifested (e.g.
cerebral oedema, spinal cord injury), with exception of non-progressing metastases
not requiring treatment with glucocorticosteroids and/or anticonvulsants within 4
weeks prior to randomization;

- Cardiovascular system pathology (congestive heart failure (CHF) stage III-IV
according to New York Heart Association (NYHA) classification, unstable angina
pectoris, myocardial infarction) within 12 months prior to randomization;

- Surgery, radiation therapy, use of any experimental medications within 14 weeks prior
to randomization;

- Age from 18 years to 70 years inclusive;

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